Summer often brings more holidays, social events, outdoor time, and natural daylight, which tends to make people far more aware of their skin than during colder months when it is easier to cover up. As the weather becomes warmer, heavier makeup can start to feel uncomfortable or sit unevenly on the skin, leading many patients to look for treatments that improve the skin itself rather than simply masking concerns.

This is one of the reasons regenerative aesthetics has become one of the fastest-growing areas in modern cosmetic medicine. Treatments such as Polynucleotides and Profhilo® work beneath the surface of the skin, helping support hydration, collagen production, skin repair, and overall skin quality.

At FACEMED in Billericay, Essex, regenerative aesthetic treatments are especially popular heading into summer for patients wanting fresher, healthier-looking skin and a natural glow they feel confident showing off in the sunshine.

What is “Glass Skin”?

The term “glass skin” originally became popular through Korean skincare trends, but the underlying goal is something we have always aimed for in aesthetic medicine.

Healthy skin reflects light differently.

When the skin is properly hydrated, smoother in texture, supported by healthy collagen, and less inflamed, it naturally appears brighter, fresher, and more radiant without relying heavily on makeup or filters.

Patients chasing glass skin are usually not looking for dramatic transformation. Most are looking for improvements such as:

• Better hydration
• Smoother texture
• Improved skin elasticity
• Reduced crepey or tired-looking skin
• Softer fine lines
• Healthier skin quality overall

This is exactly where treatments like Polynucleotides and Profhilo® work particularly well.

What Are Polynucleotides?

Polynucleotides are regenerative injectable treatments designed to improve the quality and health of the skin from within. Rather than adding volume like traditional filler, they work by supporting the skin’s natural repair processes, helping to improve hydration, collagen production, skin strength, and overall skin function over time.

In simple terms, polynucleotides encourage the skin to behave like healthier, younger skin again.

Patients often notice:

• Better hydration
• Smoother skin texture
• Improved elasticity
• Softer fine lines
• Less crepey or tired-looking skin
• Healthier overall skin quality

One of the areas where polynucleotides have become particularly popular is around the eyes. The under-eye area is delicate and can sometimes look puffy or heavy with traditional filler in the wrong patient. Polynucleotides improve skin quality in this area without adding volume, making them a popular option for patients wanting fresher-looking eyes while still looking natural.

At FACEMED, we commonly recommend polynucleotides for patients with dull, dehydrated, thinning, or early ageing skin, particularly where the goal is healthier-looking skin rather than obvious change.

What Is Profhilo®?

Profhilo® is a regenerative injectable treatment designed to improve skin hydration, firmness, and overall skin quality without changing the natural shape of the face.

It contains hyaluronic acid and spreads smoothly beneath the skin to deeply hydrate the tissue while stimulating collagen and elastin production.

Patients often describe their skin after Profhilo® as:

• Fresher
• More radiant
• Better hydrated
• Smoother
• Firmer
• Less tired-looking

The treatment is commonly used on the face, neck, décolletage, and hands, particularly in areas where the skin is starting to look dehydrated, crepey, or less elastic.

Profhilo® is popular before summer because warmer weather, sun exposure, travel, air conditioning, and dehydration can all leave the skin looking dull or flat. By improving hydration from within, the skin often appears healthier and more luminous without looking heavy or overdone.

At FACEMED, we commonly recommend Profhilo® for patients wanting subtle, natural-looking skin rejuvenation rather than dramatic change. For milder concerns, we would usually start with two treatment sessions spaced several weeks apart. In patients with more advanced skin thinning or laxity, it can be combined with other regenerative treatments to create more comprehensive collagen stimulation and longer-term skin quality improvement.

Which Treatment Is Better: Polynucleotides or Profhilo®?

Polynucleotides and Profhilo® are often complementary rather than competing treatments.

In general:

• Polynucleotides focus more on tissue repair, regeneration, and skin quality
• Profhilo® focuses more heavily on hydration and skin remodelling

Patients with thinner, fragile, crepey, or stressed skin may benefit particularly from polynucleotides.

Patients mainly concerned with dehydration, dullness, and overall glow often respond extremely well to Profhilo®.

In reality, many patients achieve the best outcomes when treatments are combined strategically.

Can Polynucleotides and Profhilo® Be Combined?

Combination treatment plans often deliver better overall skin quality improvements because different pathways are being targeted simultaneously.

For example:

• Polynucleotides may improve repair and skin resilience
• Profhilo® may improve hydration and elasticity
• Skin boosters may further enhance luminosity
• Medical-grade skincare helps maintain results at home

The approach depends on the individual patient rather than following a fixed protocol.

Younger patients with early dehydration may need very little treatment to achieve noticeable glow. Patients with more advanced skin ageing, significant sun damage, or long-term collagen loss often require a more layered regenerative approach over time.

How Are Polynucleotides and Profhilo Different From Dermal Fillers?

Traditional dermal fillers are primarily used to restore structure, contour, or volume loss. They can enhance cheeks, lips, jawlines, or facial proportions when used appropriately.

Polynucleotides and Profhilo® work very differently. They are considered regenerative or biostimulatory treatments. Rather than reshaping the face, they focus on improving the quality and function of the skin itself.

Are Polynucleotides and Profhilo® Suitable for Younger Patients?

Many patients in their late twenties and thirties are now using regenerative aesthetics preventatively rather than waiting for more advanced ageing changes to develop.

This is a very different mindset from older aesthetic trends. Rather than dramatically altering facial structure later, many patients now prefer subtle collagen support and skin maintenance earlier.

That does not mean every younger patient needs injectable treatment. Often, good skincare, SPF, hydration, and lifestyle optimisation remain the foundation. However, for patients noticing early dehydration, dullness, skin fatigue, or loss of skin quality, regenerative treatments can work extremely well as part of a preventative approach.

FAQ: Polynucleotides and Profhilo®

Do polynucleotides make your face look fuller?

No. Polynucleotides are not designed to add volume or change facial shape. They improve skin quality, hydration, and tissue repair.

How long does Profhilo® last?

Most patients notice results lasting around six months, although this varies depending on skin condition, lifestyle, and maintenance treatment.

Are polynucleotides better than filler?

They are different treatments designed for different concerns. Polynucleotides improve skin quality, while fillers restore volume and structure.

Is there downtime after Profhilo® or polynucleotides?

Most patients experience minimal downtime. Small injection marks or mild swelling can occur temporarily but usually settle quickly.

Can you have Profhilo® and polynucleotides together?

Yes. In many patients, combination treatment plans create better overall skin quality improvements than using one treatment alone.

At what age should you start regenerative treatments?

There is no fixed age. Suitability depends more on skin condition, hydration levels, collagen loss, and individual goals than age alone.

Considering Regenerative Aesthetics in Essex?

At FACEMED in Billericay, Essex, regenerative aesthetic treatments are tailored carefully according to skin quality, hydration levels, collagen loss, and long-term treatment goals.

Whether you are looking to improve dullness before summer, soften early signs of ageing, restore healthier skin quality, or create a more natural glow without relying on heavy makeup, treatments such as Polynucleotides and Profhilo® can often form part of a personalised treatment plan.

Book a consultation so we can assess your skin properly, discuss the most appropriate options for your concerns, and create a treatment approach that looks natural both now and long term.